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Clotting Factors in Supernatant Plasma Following Cryoprecipitation
Author(s) -
Roth G. J.,
Tobias K. I.
Publication year - 1974
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1974.tb04509.x
Subject(s) - clotting factor , chemistry , blood coagulation factors , platelet , immunology , medicine , coagulation
The supernatant plasma which remains after cryoprecipitation is a useful component for transfusion therapy. However, from prior studies it was unclear how well plasma clotting factors were preserved following cryoprecipitation. Coagulation factor assays were performed on fresh plasma, supernatant plasma after removal of cryoprecipitate, and the same supernatant plasma following re‐freezing and thawing. Factor VIII and fibrinogen levels fell considerably after removal of cryoprecipitate, but there was also a significant decline in factor V. Refreezing and thawing the supernatant plasma had little effect on clotting factors.