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In Vitro Analysis of Platelet Function During Storage of Platelets from Plasmapheresed Donors
Author(s) -
Moore G. L.,
Mallin W. S.,
Roberts S. C.,
Failla M. L.,
Gray J. L.
Publication year - 1973
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1973.tb05458.x
Subject(s) - platelet , in vitro , plasmapheresis , blood preservation , function (biology) , chemistry , andrology , immunology , medicine , biology , biochemistry , microbiology and biotechnology , antibody
Several in vitro platelet function assays were examined. Two units of platelets from each of ten volunteer donors were obtained by plasmapheresis, stored three days, and examined by various functional parameters. The second unit of platelets from an individual had generally lower functional parameters than the first, suggesting a subtle physiological change in the donors' circulation between the time of drawing the first and second units. For in vitro comparisons, this difference was overcome by a pooling procedure. Platelet storage was examined at room temperature and at 4 C.