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Australia Antigen and Antibody in Blood Donors and Patients with Blood Disorders
Author(s) -
Hsia S.,
Chen S. C.,
Shen F. C.,
Shih B. Y.
Publication year - 1973
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1973.tb05446.x
Subject(s) - complement fixation test , medicine , antibody , immunology , antigen , immunodiffusion , blood disorder , serology
Screening for Australia antigen (HBAg) and antibody (HBAb) in normal blood donors and patients with blood disorders or leprosy was performed by both immunodiffusion and complement fixation. HBAg was detected among blood donors, but patients with blood disorders had significantly higher HBAg incidence. HBAb was found to be distinctive in patients with blood disorders. A considerable number of patients were found to have both HBAg and HBAb in their blood. Quantitative measurement of positive HBAg and HBAb was simultaneously made with complement fixation.