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Fetal Cell Counting as a Guide to Prevention of Rh Sensitization
Author(s) -
Clayton E. M.,
Birdwell E. D.,
Gregory M. G.
Publication year - 1973
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1973.tb04472.x
Subject(s) - sensitization , fetus , medicine , pregnancy , immunology , globulin , immune system , obstetrics , biology , genetics
Administration of a standard dose of Rh immune globulin in the immediate postpartum period is adequate to protect 93 per cent of the Rh negative mothers that would otherwise become sensitized. It is now possible by utilizing fetal cell counts to identify those patients in which the standard dose of immune globulin is inadequate for protection. A method for easy and accurate identification of potential failures is described.