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Efficacy of the Latham Blood Processor To Perform Plateletpheresis
Author(s) -
Szymanski I. O.,
Patti K.,
Kliman A.
Publication year - 1973
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1973.tb04468.x
Subject(s) - plateletpheresis , platelet , extracorporeal circulation , hematocrit , medicine , centrifugation , blood collection , anesthesia , surgery , apheresis , chemistry , chromatography , emergency medicine
Platelets were separated during extracorporeal circulation by the method of Tullis et al . in the Latham Blood Processor equipped with a 375 ml disposable centrifuge bowl. The average yield of platelets recovered from each 710 ml unit of blood was 0.665 × 10 11 ± 0.244 × 10 11 (± 1 S. D.) N = 105, corresponding to an efficiency of 45.8 ± 12.4 per cent. Platelets were also separated during extracorporeal circulation by a modification of the method. In this technic the final platelet concentrate contained about 50 ml of red blood cells that were removed by an additional centrifugation. The average quantity of platelets recovered from each 710 ml of blood was 1.23 × 10 11 ± 0.285 × 10 11 (± I S. D.) corresponding to an efficiency of removal of 69.5 ± 14.6 per cent (± I S. D.). The modified method permitted a collection of large numbers of platelets from single donors in a relatively short time. Donor effects of the procedure were insignificant. Mild to moderate donor reaction consisting of chilling and hypotensive reactions occurred in three of 145 donors. Transient decreases occurred in hematocrit and platelet count. No untoward effects were observed following repeated procedures.