Premium
Hemostatic Abnormalities in Heroin Addicts
Author(s) -
Puszkin E.,
Gutfreund D.,
Aledort L. M.
Publication year - 1972
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1972.tb00015.x
Subject(s) - epinephrine , heroin , medicine , platelet , thrombin , heroin dependence , addiction , anesthesia , pharmacology , psychiatry , drug
Eight of ten heroin addicts demonstrated abnormalities of platelet aggregability. Abnormalities were seen with ADP, epinephrine, collagen and, in particular, thrombin. The bleeding time was prolonged in three of these eight addicts. The acetyl moiety of heroin, 6‐monoacetylmorphine, may be responsible for these abnormalities.