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Antenatal Transplacental Hemorrhage
Author(s) -
Grobbelaar B. G.,
Mostert D.
Publication year - 1970
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1970.tb00708.x
Subject(s) - transplacental , medicine , pregnancy , immunization , titer , obstetrics , antibody , fetus , pediatrics , immunology , placenta , biology , genetics
A transplacental hemorrhage of approximately 10 ml occurred at the 29th week of the first pregnancy of a woman carrying twins. The administration of 400 μg Rh immunoglobulin 96 hours later failed to prevent primary immunization. Traces of saline‐reacting anti‐Rh 0 (D) were detectable by the 32nd week, increasing to a titer of 1 : 64 by the 37th week of pregnancy. The possibility that antenatal administration of Rh immunoglobulin may enhance the risk of primary immunization is considered.