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Familial Occurrence of Increased Activity of Blood‐group A in Serum
Author(s) -
Ottensooser F.,
Araujo J. T.,
Rosales T.
Publication year - 1970
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1970.tb00694.x
Subject(s) - hemoglobin , medicine , anemia , blood group antigens , immunology , abo blood group system , physiology , antibody
Increased activity of blood‐group substance A was found over a three‐month period in the serum of a Negro who was group A 1 and a secretor of A and H. Two of his children, A 1 B secretors, possessed the same feature, but two other children (A 1 and A 1 B secretors) did not. The three persons with increased serum values for A all had hemoglobin S; the two others did not. However, there does not appear to be a close association between the two traits because the sera of A, secretors who were parents of children with sickle‐cell anemia contained normal amounts of A activity.