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Pooled Platelet Concentrates Prepared in a New Blood Bank Centrifuge
Author(s) -
Miller W. V.,
Gillem H. G.,
Yankee R. A.,
Schmidt P. J.
Publication year - 1969
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1969.tb04932.x
Subject(s) - platelet , centrifuge , whole blood , platelet concentrate , blood bank , platelet transfusion , apheresis , abo blood group system , medicine , chemistry , centrifugation , surgery , chromatography , immunology , physics , nuclear physics , medical emergency
Pools of platelet‐rich plasma, prepared by the split‐ACD technic at the donor facility, were passed through a special (ADL) centrifuge bowel to continuously trap platelets within the bowl as platelet‐poor plasma was removed. The platelets were concentrated in a final volume of 125 to 150 ml. With the bowl used, flow rates of about 50 ml/min at 1,200 × g allowed concentration of 80 per cent of the platelets from the original plasma. Platelet clumping did not occur despite admixture of ABO blood groups. Recovery in vivo was equal to that observed for platelets in conventional concentrates. Divided doses of these platelet concentrates were reserved for multitransfused patients because pooling increases the risk of transmitting hepatitis. This method is a rapid, effective, semiautomated adjunct to blood‐component preparation in hospital blood banks.