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Agglutinins for “Null” Red Blood Cells
Author(s) -
McGinniss M. H.,
Kaplan H. S.,
Bowen A. B.,
Schmidt P. J.
Publication year - 1969
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1969.tb04911.x
Subject(s) - agglutination (biology) , antibody , autoimmune hemolytic anemia , antigen , immunology , null cell , red blood cell , anemia , in vitro , red cell , hemoglobin , medicine , biology , biochemistry , cell culture , genetics
The sera from two patients with unexplained anemia gave a pattern of agglutination in vitro which was the converse of that described for Rh‐like antibodies associated with autoimmune hemolytic anemia. These sera reacted with not only Rh null red blood cells but also U negative, Bombay and other cells lacking in usual agglutinogens. They appeared to contain antibodies directed against antigenic structures which are either absent or covered on the surface of red blood cells of the more usual types.

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