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Detection and Characterization of Blood Group Antigens on Untransformed Human Amnion Cells
Author(s) -
Friedhoff F.,
Kuhns W. J.
Publication year - 1968
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1968.tb02416.x
Subject(s) - amnion , agglutination (biology) , antigen , andrology , group b , group a , immunology , biology , microbiology and biotechnology , medicine , pregnancy , fetus , genetics
Amnion cells, primary and in culture, along with the infant's own erythrocytes, were tested by mixed agglutination for blood groups A, B, H, M, N, Tj a , Rh o (D), Yt a , I and i. Studies were carried out on cell cultures ranging in age from one day to 39 days. Only A, B, H, Tj a , I and i could be demonstrated on amnion cells. Decrease in the number of cells positive for Tj a , and possibly for A and B, was observed in the course of cell passages. In cultures positive for H, the percentage of positive cells, although small, generally continued as long as the culture was studied.