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Transfusion of Fresh Platelet Concentrates to Adult Patients with Thrombocytopenia
Author(s) -
Cavins J. A.,
Farber S.,
Roy A. J.
Publication year - 1968
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1968.tb02382.x
Subject(s) - plateletpheresis , medicine , platelet , platelet transfusion , adverse effect , platelet concentrate , blood transfusion , anesthesia , surgery , apheresis
Fresh platelet concentrates were given to 18 adult patients on 68 occasions without adverse effect. The concentrates were prepared by means of a closed‐system plateletpheresis technic which permitted rapid and frequent bleeding of donors. There was a direct relationship of the amount of platelets infused to the mean posttransfusion increment. Excellent hemostatic effect was noted in 84% of patients with active bleeding when the platelet increment was 40,000/mm 3 or better. Transfusion of large numbers of platelet concentrates is effective in controlling or averting bleeding in adults with thrombocytopenia and is recommended on a therapeutic and prophylactic basis.