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Substances in Serum Causing Interference with Blood Group Determination
Author(s) -
Treacy M.,
Geiger J.,
Goss M. F.
Publication year - 1967
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1967.tb04883.x
Subject(s) - antiserum , blood group antigens , antigen , medicine , group a , chemistry , immunology , chromatography
Excessively high concentrations of soluble substances which inhibit anti‐A or anti‐B have been reported previously in the sera of patients with certain disease conditions. This report describes four new cases in which sufficient soluble substance was present in a suspension of unwashed red cells to completely neutralize the antiserum used for blood group determination. The soluble antigen content of these sera was compared with that of normal sera by inhibition tests.