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A “New” Infrequent Red Cell Antigen, Rd (Radin)
Author(s) -
Rausen Aaron R.,
Rosenfield Richard E.,
Alter Aaron A.,
Hakim Shirin,
Graven Stanley N.,
Apollon Cora J.,
Dallman Peter R.,
Dalziel Joan C.,
Konugres Angelyn A.,
FRANCis Betty,
Gavin June,
Cleghorn Thomas E.
Publication year - 1967
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1967.tb04864.x
Subject(s) - abo blood group system , antigen , haptoglobin , haemolytic disease , immunology , antibody , red blood cell , biology , isoantibodies , blood group antigens , red cell , rh blood group system , incidence (geometry) , pregnancy , medicine , microbiology and biotechnology , genetics , fetus , physics , optics
Five examples of a “new” blood group antibody, anti‐Rd (Radin), are reported. The corresponding antigen, Rd, is infrequent and does not correspond to any other known “low‐incidence” antigen. Family studies indicate that Rd is an autosomal dominant character which does not belong to the ABO, MNSs, Rh, Lutheran, Kell or Kidd blood group systems. Furthermore, the gene determining Rd is not closely linked to either the haptoglobin or red cell acid phosphatase loci. Anti‐Rd caused mild to moderate hemolytic disease of the newborn in all five families and has appeared with the first pregnancy.