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Three Examples of Anti‐Lu b and Related Data
Author(s) -
Molthan Lyndall,
Crawford Mary N.
Publication year - 1966
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1966.tb04782.x
Subject(s) - antigenicity , incidence (geometry) , medicine , immunology , antibody , mathematics , geometry
Three new examples of anti‐Lu b , two detected in 1963 and the third in 1965, are described. The first example was responsible for repeated hemolytic transfusion reactions, the second and third though associated with pregnancy do not appear to have been responsible for a clinical problem. 14,802 random donor bloods were typed with the first example and eight Lu(b—) bloods identified, the incidence being 0.057%. Lutheran typings on 95 individuals related to propositi who are Lu(a+b—), Lu(a+b+), and Lu(a—b—) revealed nine new Lu(b—) persons. Medical historical data on 85 known Lu(a+b—) persons are included in an attempt to evaluate the antigenicity of the Lu b factor. The incidence of the phenotype, Lu(a+b+), in 556 Negroes was found to be 4.86%.