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The Preservation of Red Cell ATP
Author(s) -
Beutler Ernest,
Duron Olga
Publication year - 1966
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1966.tb04709.x
Subject(s) - preservative , phosphate , chemistry , sodium , adenosine triphosphate , biochemistry , food science , organic chemistry
The addition of high concentrations of phosphate ion have been found to enhance markedly the stability of ATP of red cells stored at 4 C. A marked initial rise of ATP levels was followed by a subsequent gradual decline when phosphate in concentrations of .05 M to .3 M was included in preservative media containing adenine. A second rise in the concentration of ATP was observed if the pH of the sample was adjusted by the addition of sodium carbonate. The addition of phosphate in high concentrations to preservative media may prove to be of practical significance.