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The Disposition of STS* Reactive Blood in a Transfusion Service
Author(s) -
Walker Richard H.
Publication year - 1965
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1965.tb02924.x
Subject(s) - medicine , syphilis , titer , serology , blood donor , infectivity , blood transfusion , immunology , rapid plasma reagin , antibody , human immunodeficiency virus (hiv) , virus , treponema
Ninety‐eight units of Serological Test (or Syphilis (STS) reactive blood were quarantined for one week and transfused into 90 patients. Recipients transfused with donor blood having reagin titers less than eight dils by the Venereal Disease Research Laboratory (VDRL) quantitative tube test failed to have detectable reagin in their sera following transfusion. Four to ten days was the longest period observed for the disappearance of passively trans erred reagin in a patient who was transfused with donor blood having a titer of 64 dils. Fluorescent Treponemal Antibody (FTA) tests were performed on two patients 2 to 3 months after tranfusion and were negative. The fallibility of the conventional STS testing on donor blood is discussed and its failure to demonstrate infectivity is emphasized. Attention is called to the potential danger of fresh blood, especially platelet preparations.