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Increased Red Cell Destruction in the Absence of Demonstrable Antibodies in Vitro
Author(s) -
Loghem J. J.,
Hart Mia,
Moes Mieke,
Borne A. E. G. Kr. von
Publication year - 1965
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1965.tb01199.x
Subject(s) - hypogammaglobulinemia , antibody , immunology , humoral immunity , in vitro , medicine , red blood cell , immunity , red cell , blood transfusion , isoantibodies , immune system , chemistry , biochemistry
Survival studies performed in human subjects, using Cr 51 ‐labeled donor red cells, showed that in the absence of demonstrable humoral iso‐antibodies iso‐immunity can still exist. Three groups of persons were investigated: 1) patients with hypogammaglobulinemia; 2) donors with blood group A lacking anti‐B; 3) patients with hemolytic transfusion reactions.