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Identification of a Specific Leukocyte Antigen: Another Presumed Example of 5 b
Author(s) -
Lalezari Parviz,
Bernard Georgette E.
Publication year - 1965
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1965.tb01148.x
Subject(s) - antigen , antibody , microbiology and biotechnology , platelet , immunology , biology , gene , allele , genetics
A leukocyte agglutinating antibody obtained from a multiparous normal female was studied. By means of cross‐absorption and antibody elution methods, it was established that this antibody detected a single leukocyte antigen, designated as “Ke.” The data suggest a gene frequency of 0.8 for “Ke” and 0.2 for “ke,” the postulated allelic gene. The antigen is shared by granulocytes, lymphocytes‐monocytes, eosinophils and also platelets, but is absent from red cells. The cross reaction studies indicate that this antigen may be identical with group 5 b already described by Van Rood.
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