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The Use of an Albumin‐Enhanced Indirect Antiglobulin System to Detect Immune Anti‐A and Anti‐D in the Serum of the Newborn
Author(s) -
Hamrick Lois
Publication year - 1964
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1964.tb02893.x
Subject(s) - abo blood group system , immunology , coombs test , immune system , medicine , hemolytic disease of the newborn (abo) , albumin , haemolytic disease , antibody , pregnancy , fetus , biology , genetics
A case of hemolytic disease of the newborn is presented. Immune anti‐A and anti‐D were detected in the serum of the mother and the infant. The use of the albumin‐enhanced antiglobulin system proved effective in detecting anti‐A and anti‐D in the infant's serum after all other systems had failed. The need for caution in inferring ABO incompatibility alone in the presence of a strongly reactive direct Coombs test is illustrated.