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Third Example of a Human “D‐like” Antibody or Anti‐LW
Author(s) -
Swanson Jane,
Matson G. Albin
Publication year - 1964
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1964.tb02868.x
Subject(s) - antibody , microbiology and biotechnology , chemistry , immunology , biology
The third example of human “D‐like” (LW) antibody is reported. The serum from an rr (cde) patient (VW) agglutinates D positive cells strongly but D negative cells to a lesser degree. The antibody does not react with the patient's own cells or with those of her R 1 r (CDe/cde) sister. When VW's serum is absorbed by ordinary rr (cde) cells, the antibody is removed for D positive and D negative cells and the eluate from the cells contains “D‐like” (LW) antibody. When VW's (“anti‐D‐like”) serum is absorbed by “D‐like” (LW) negative cells, antibody for D positive and D negative cells is not removed and the eluate from these cells contains no antibody.