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Antigen Reactivity in Pilot Tube Blood Specimens: Clotted Blood vs. Blood Stored in Acid‐Citrate‐Dextrose
Author(s) -
Sussman Leon N.,
Butler John
Publication year - 1964
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1964.tb02858.x
Subject(s) - medicine , blood preservation , blood bank , whole blood , expiration date , vial , antigen , surgery , immunology , anesthesia , chemistry , chromatography , andrology , emergency medicine , food science
Present blood bank practices of using either clotted blood or ACD pilot tubes stored at 4 C. give equally satisfactory antigen preservation up to 21 days of storage. Thereafter, there is a distinct difference, in that the pilot tube blood sample stored in ACD retains antigen reactivity for a longer period of time than does the blood stored as a clot. The added difficulty of the repeated washings of the ACD stored sample required to remove traces of plasma and anticoagulant must be considered in evaluating the advantages of either system. The anticipated use of storage formulae capable of maintaining better preservation of the stored blood for periods up to 42 days requires that the problem of the “proper” pilot tube be reconsidered. In this light, the preliminary serum screening of all recipients, using fresh pools of red cells bearing all the important known blood factors, becomes valuable. It is therefore recommended that the screening test be adopted by all blood banks and that particularly careful attention be directed to crossmatching tests on stored blood approaching the expiration date.