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Phosphorylated Carbohydrate Intermediates of the Human Erythrocyte during Storage in Acid Citrate Dextrose:
Author(s) -
Shaker A. William,
Trombold John S.
Publication year - 1964
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1964.tb02842.x
Subject(s) - inosine , adenosine , adenosine triphosphate , chemistry , adenine nucleotide , biochemistry , carbohydrate , adenosine diphosphate , blood preservation , adenosine monophosphate , chromatography , nucleotide , medicine , andrology , platelet , platelet aggregation , gene
Blood was stored at 4 C. in ACD without additive or supplemented with adenine, inosine, inosine‐adenine, or adenosine. After six weeks of storage the carbohydrate intermediates of the erythrocytes were studied by column chromatography. Adenosine triphosphate (ATP) and 2,3‐diphosphoglycerate (DPG) had disappeared from blood stored without additive or with adenine. Both ATP and DPG remained in erythrocytes stored with the other additives. Concentration of ATP was highest in blood stored with inosine‐adenine, and the level of DPG was highest with the addition of adenosine to the storage solution.