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Complement Activity in Sera from Normal Adult Blood Donors: Its Relation to Blood Group, Rh*** (D) Type, Sex, Age and Weight
Author(s) -
Marucci Americo A.,
Chapman Orren D.
Publication year - 1964
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1964.tb02826.x
Subject(s) - complement (music) , titer , immunology , blood type (non human) , medicine , biology , antibody , abo blood group system , phenotype , biochemistry , complementation , gene
Serum samples from 1,258 normal adult blood donors were assayed for complement activity. The average complement titer for the entire sample was 38.14. There was no difference in complement activity with respect to sex, blood group or Rh***(D) type. The level of circulating complement appears to be higher in older humans and in heavier individuals. In this kind of experimentation, the need for a standard complement for assay of different batches of sheep erythrocytes is emphasized.