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Red Cell Preservation in Citrate‐Phosphate‐Dextrose and in Acid‐Citrate‐Dextrose
Author(s) -
Bowman Herbert S.
Publication year - 1963
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1963.tb04658.x
Subject(s) - red cell , blood preservation , hemoglobin , red blood cell , chemistry , medicine , andrology , biochemistry
In a series of red cell survival experiments, autotransfusions of erythrocytes drawn in CPD solution maintained better viability than those in ACD solution (NIH, Formula A), after 28 days continuous storage at 4 ± 1 C. Augmented erythrocyte preservation in CPD was accompanied by lesser amounts of hemoglobin in the plasma of the donor blood, and in the recipient's plasma at 15 minutes after the transfusion. It was also shown by an appreciably higher 24‐hour posttransfusion erythrocyte survival and by a longer half‐life beyond the initial 24 hours as estimated by T/2, Cr‐51.