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The Relation of Human and Cattle Blood Groups
Author(s) -
Stone W. H.
Publication year - 1962
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1962.tb00217.x
Subject(s) - biology , sterility , titer , agglutination (biology) , antibody , rh blood group system , hemagglutination , immunology , genetics
The blood groups of humans and of cattle are very similar, even though cattle cells are typed by a hemolytic test and human cells by an agglutination test. In each species, over 50 antigenic factors are detectable and nine to ten genetically independent systems are known. The J substance of cattle and the A substance of humans are serologically and chemically related. Both occur on the erythrocytes and in body fluids and their respective naturally occurring antibodies show seasonal variation in titer. The B system of cattle contains over 200 phenogroups detected with one or more of 20‐odd reagents; the Rh system of humans also contains over 200 phenogroups detected with ten to 12 standard reagents. As knowledge of the Rh system evolves, it more nearly parallels the B system of cattle. Hemolytic disease does not occur in cattle either naturally or by active or passive immunization. Erythrocyte chimerism is much more frequent in cattle than in humans, but sterility of females born co‐twin to males has been observed in cattle only. The excess of MN heterozygotes from intercross matings in humans has its parallel in the excess of Z heterozygotes in cattle, both phenomena are presumably associated with a heterotic effect.