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Citrate‐Phosphate‐Dextrose Solution for Preservation of Human Blood: A Further Report
Author(s) -
Gibson John G.,
Gregory Clinton B.,
Button Lawrence N.
Publication year - 1961
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1961.tb00059.x
Subject(s) - medicine , blood preservation , expiration date , whole blood , blood transfusion , packed red blood cells , surgery , chemistry , physiology , food science
A comparison of clinically significant in vitro characteristics of ACD and CPD blood is presented. In clinical trials conducted at three hospitals, 586 units of blood collected in CPD in plastic bags were utilized for 622 individual treatments as single units or subdivided aliquots of whole blood, and as packed red cells in 332 patients. The expiration period was 28 days, and five bloods were discarded as outdated. There was one reported pyrexial reaction and one proven bacterial contamination. Forty‐two per cent of the bloods or components were issued during the first week, 43 per cent during the second and third weeks, and 15 per cent during the fourth week of storage. Of the total bloods or components issued, 9 per cent of the whole bloods, 25 per cent of the subdivided blood aliquots, and 23 per cent of the packed red cells were transfused during the fourth week of storage. No difficulty with clotting was observed during collection, storage, or transfusion.