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A Critique of the Theoretical Hazard of Inter vs . Intra‐Racial Transfusion *
Author(s) -
Giblett Eloise R.
Publication year - 1961
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1961.tb00048.x
Subject(s) - antigen , antibody , blood transfusion , medicine , transfusion reaction , potency , immunology , biology , genetics , in vitro
From the frequencies of the red cell antigens of Caucasians and American Negroes, the possibilities of antigenic exposure from inter and intra‐racial transfusion of blood were calculated. The figures obtained were then modified to take into consideration the relative potency of the individual antigens as well as the behavior of their antibodies. The results lend no support to the alleged advantage of intra‐racial over inter‐racial transfusion, since the order of magnitude of the antibody stimulation risk from all four kinds of transfusion is the same. From the standpoint of patient safety, emphasis should be placed on the performance of a sensitive compatibility test, rather than on a consideration of the racial origin of either the donor or the recipient.