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Studies on Bank Blood Collected and Stored under Various Conditions with Particular Reference to Its Use in Open Heart Surgery
Author(s) -
Perkins Herbert A.,
Rolfs Mary R.,
Acra D. J.
Publication year - 1961
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1961.tb00031.x
Subject(s) - platelet , blood collection , medicine , blood bank , whole blood , blood preservation , heparin , fresh frozen plasma , hemoglobin , surgery , clotting factor , anesthesia , physiology , emergency medicine
A few of the factors responsible for the preservation of the characteristics of fresh blood during storage have been studied, with particular reference to the provision of donor blood for open heart surgery. It has been indicated that present data leave us no reason to think that platelet viability and the level of labile clotting factors in stored blood will be any different whether the blood is collected by gravity or with the aid of vacuum. Changes in bloods stored at 4C. for a 21 day period were investigated with ACD, heparin and Edglugate‐Mg as the anticoagulants. The studies on heparinized blood suggest that after two or three days, the fall in platelets and the rise in plasma potassium and hemoglobin are so much greater than occur in ACD that storage for longer periods than that will probably never be safe. On the other hand, in vivo studies indicate that 24‐hour‐old heparinized blood is just as safe to use as four‐hour‐old blood. Edglugate‐Mg was developed in an effort to get around the limited storage period of heparinized blood. Results reported here show that plasma potassium levels rise very rapidly in this type of blood. Platelets are not well‐preserved in vitro , and Factor V levels are apparently low soon after collection.