Premium
Physical Medicine and Rehabilitation (88)
Author(s) -
Suputtitada A.
Publication year - 2001
Publication title -
pain practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 58
eISSN - 1533-2500
pISSN - 1530-7085
DOI - 10.1111/j.1533-2500.2001.1011-88.x
Subject(s) - spasticity , medicine , cerebral palsy , cerebral palsied , rehabilitation , botulinum toxin , physical medicine and rehabilitation , modified ashworth scale , gait , physical therapy , spastic , muscle contracture , ankle , hypertonia , diplegia , ambulatory , anesthesia , surgery
Managing spasticity in pediatric cerebral palsy using a very low dose of botulinum toxin type A: preliminary report. (Chulalongkorn University Hospital, Bangkok, Thailand) Am J Phys Med Rehabil 2000;79:320–326. This study was conducted to determine if very low doses of botulinum toxin type A (BTX‐A) could reduce spasticity and improve gait in cerebral palsied children when combined with rehabilitation therapy. The trainable (IQ> 80), ambulatory, spastic diplegic or hemiplegic cerebral palsied children, with no fixed contractures in at least one limb, were selected for this study. Patients with a score of 3 on a modified Ashworth scale received 0.5 units of BTX‐A/kg/muscle. Patients with an Ashworth score of 4 received 1.0 BTX‐A/kg/muscle. After BTX‐A injection, all patients received rehabilitation therapy and plastic ankle and foot orthoses for walking. Both groups exhibited improvement in Ashworth score and in gait within 72 h of injection with botulinum toxin. Beneficial effects persisted for 10 to 12 months in most patients, with 3 patients exhibiting benefits for at least 20 months. Conclude that a very low dose of BTX‐A combined with rehabilitation therapy resulted in a long‐lasting decrease in spasticity and an improvement in gait in children with cerebral palsy.