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Ex Vivo Evaluation of Canine Lung Biopsy Techniques
Author(s) -
Marvel Sarah,
Monnet Eric
Publication year - 2013
Publication title -
veterinary surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 79
eISSN - 1532-950X
pISSN - 0161-3499
DOI - 10.1111/j.1532-950x.2013.01108.x
Subject(s) - medicine , cadaveric spasm , lung , leak , nuclear medicine , surgery , population , environmental health , environmental engineering , engineering
Abstract Objective An ex vivo comparison of thoracoscopic lung biopsy techniques in dogs. Study Design Experimental. Sample Population Cadaveric canine lung lobes. Methods Lungs were inflated to 10 cmH 2 O. After collecting biopsies 3 cm from the edge of lung lobes, leak pressures were recorded as inflation pressure was increased to 40 cmH 2 O. Pre‐tied loop ligature, square knot (SQ), modified 4S Roeder knot (M4SR) with glycomer 631 and polyglactin 910 size 0 and 2‐0 were used in addition to EndoGIA 45–2.5 mm (Covidien, Norwalk, CT) and a vessel sealant device (VSDS single and VSDD double seal). Six biopsies were performed with each of these modalities. Results Median airway pressure at which leakage occurred was 28 (20–34) cmH 2 O for EndoGIA 45; 33 (14–40) for VSDD; and 33 (10–40) for VSDS while other groups reached a median pressure of 40 cmH 2 O ( P < .0001). Leakage occurred at 20 cmH 2 O in 1 sample with the EndoGIA and the VSDS, and in 2 with the VSDD while leakage did not occur in any other group ( P = .36). Leakage occurred at 30 cmH 2 O in 1 specimen each of the 0‐polyglactin SQ, 2‐0 glycomer 631 M4SR, 2‐0 polyglactin M4SR, and 2‐0 Surgitie (Covidien, Norwalk, CT); 2 with the VSDS; and 3 with the EndoGIA and the VSDD while leakage did not occur in any other group ( P = .26). Conclusions All tested techniques seemed safe except the vessel sealant device since it did not consistently seal every biopsy and leaked at pressures <20 cmH 2 O.