Premium
The Effect of Neuromuscular Blockade on Canine Laparoscopic Ovariectomy: A Double‐Blinded, Prospective Clinical Trial
Author(s) -
Bart Van Goethem,
Sebastiaan Alexander van Nimwegen,
Ies Akkerdaas,
Joanna Claire Murrell,
Kirpensteijn Jolle
Publication year - 2012
Publication title -
veterinary surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 79
eISSN - 1532-950X
pISSN - 0161-3499
DOI - 10.1111/j.1532-950x.2011.00962.x
Subject(s) - medicine , neuromuscular blockade , double blinded , clinical trial , blinded study , blockade , anesthesia , pathology , alternative medicine , placebo , receptor
Objective To evaluate the effect of neuromuscular blockade ( NMB ) on surgical time and various anesthetic variables during laparoscopic ovariectomy in dogs. Study Design Prospective, double‐blinded, randomized clinical trial. Animals Female dogs (n = 40). Methods Laparoscopic ovariectomy by bipolar electrocoagulation was performed by 1 surgeon using a standardized protocol, where 1 ovary was removed under NMB , and the other without NMB . Surgical and anesthetic (respiratory and circulatory) variables were recorded for predetermined procedural stages and were statistically evaluated. Results Mean total surgical time was 25.1 ± 6.3 minutes (range, 16–47 minutes). With NMB , mean duration of surgical excision of the ovary (5.7 ± 2.3 minutes) was not significantly changed compared to ovariectomy without NMB (5.9 ± 1.9 minutes). Arterial blood pressure was the only recorded anesthetic variable that significantly changed under NMB (5% decrease). Occurrence of intraoperative complications did not differ. In obese dogs, total surgical time was increased by 22%. Other variables, including occurrence of intraoperative mesovarial bleeding did not influence surgical duration. Conclusions NMB did not significantly improve laparoscopic ovariectomy times and except for a 5% decrease in arterial blood pressure did not change any of the evaluated anesthetic and surgical variables.