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Butorphanol Does Not Reduce the Minimum Alveolar Concentration of Halothane in Dogs
Author(s) -
QUANDT JANE E.,
RAFFE MARC R.,
ROBINSON ELAINE P.
Publication year - 1994
Publication title -
veterinary surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 79
eISSN - 1532-950X
pISSN - 0161-3499
DOI - 10.1111/j.1532-950x.1994.tb00462.x
Subject(s) - butorphanol , medicine , halothane , anesthesia , minimum alveolar concentration , heart rate , blood pressure , sevoflurane
This study evaluated the effect of butorphanol tartrate, a synthetic opioid agonist‐antagonist, on halothane minimum alveolar concentration (MAC) in dogs. Baseline halothane MAC was determined in each of six dogs. Butorphanol was administered and halothane MAC was redeter‐mined. Each dog received butorphanol at 0.2, 0.4, and 0.8 mg/kg intravenously at 1 week intervals. Heart rate and arterial blood pressure decreased after butorphanol administration, but returned to baseline by 50 minutes. There was little effect on respiratory parameters. A halothane‐sparing effect was not noted with any butorphanol dose.