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Comparison of Cerebrospinal Fluid Pressure in Propofol‐and Thiopental‐anesthetized Eucapnic Dogs
Author(s) -
WOOTEN THOMAS L.,
LOWRIE CHARLES T.
Publication year - 1993
Publication title -
veterinary surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 79
eISSN - 1532-950X
pISSN - 0161-3499
DOI - 10.1111/j.1532-950x.1993.tb01690.x
Subject(s) - medicine , propofol , anesthesia , cerebrospinal fluid pressure , anesthetic , cerebrospinal fluid , intracranial pressure , thiopental sodium
Cerebrospinal fluid pressure (CSF P ) was measured as part of the neurologic assessment of dogs with suspected intracranial disease. Because propofol has not been shown to cause an increase in intracranial pressure in humans, the authors examined its effect on (CSF P ) in dogs to determine if it would be an appropriate substitute for thiopental as an anesthetic agent for the measurement of CSF P . The CSF pressure in eucapnic propofol‐anesthetized dogs (105 ± 5.6 mm H P O) was not significantly different (p < .05) from CSF P in eucapnic thiopental‐anesthetized dogs (103.8 ± 6.6 mm H P O).