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Oxalate Nephrosis and Renal Sclerosis After Renal Transplantation in a Cat
Author(s) -
GREGORY C. R.,
OLANDER H. J.,
KOCHIN E. J.,
GOURLEY I. M.,
COUSYN D.,
LEVY J.
Publication year - 1993
Publication title -
veterinary surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 79
eISSN - 1532-950X
pISSN - 0161-3499
DOI - 10.1111/j.1532-950x.1993.tb00385.x
Subject(s) - medicine , transplantation , nephrosis , primary hyperoxaluria , oxalate , urology , chronic renal failure , renal function , renal transplant , endocrinology , chemistry , organic chemistry
A 10‐year‐old castrated domestic shorthair cat received two renal allografts, 14 days apart, for the treatment of chronic renal failure. Oxalate nephrosis developed in both allografts, and they became nonfunctional. During the transplantation period, the cat was not exposed to exogenous sources of oxalate, and there was no evidence of primary type 2 hyperoxaluria before surgery. Urologic surgery, in particular renal transplantation, has been identified as a factor that can precipitate renal failure in human patients with decompensated renal function and hyperoxaluria. If hyperoxaluria was present before surgery in this cat, it was most likely caused by increased absorption or decreased metabolism of dietary oxalate.