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Gastric Conduit Urinary Diversion in Normal Dogs Part II, Hypochloremic Metabolic Alkalosis
Author(s) -
McLOUGHLIN MARY A.,
WALSHAW RICHARD,
THOMAS MICHAEL W.,
HAUPTMAN JOE G.
Publication year - 1992
Publication title -
veterinary surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 79
eISSN - 1532-950X
pISSN - 0161-3499
DOI - 10.1111/j.1532-950x.1992.tb00008.x
Subject(s) - medicine , electrical conduit , metabolic alkalosis , urinary diversion , cystectomy , bladder cancer , cancer , mechanical engineering , engineering
Gastric conduit urinary diversion was performed in 10 dogs after complete cystectomy. Four dogs were euthanatized on day 30 because of hypochloremic metabolic alkalosis and renal failure. Hematologic and biochemical changes in six dogs evaluated for 120 days were compatible with hypochloremic metabolic alkalosis. The continuous loss of hydrochloric acid from the gastric conduit resulted in significant increases in arterial blood pH, P a CO 2 , anion gap, TCO 2 , and the concentration of Hco3‐. There were significant decreases in P a O 2 and the serum concentrations of chloride and potassium. Deterioration of renal function resulted in all dogs. It was concluded that hypochloremic metabolic alkalosis makes gastric conduit urinary diversion unsatisfactory for clinical use in dogs.