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Effects of Atropine and Glycopyrrolate on Esophageal, Gastric, and Tracheal pH in Anesthetized Dogs
Author(s) -
ROUSH JAMES K.,
KEENE BRUCE W.,
EICKER STEVEN W.,
BJORLING DALE E.
Publication year - 1990
Publication title -
veterinary surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 79
eISSN - 1532-950X
pISSN - 0161-3499
DOI - 10.1111/j.1532-950x.1990.tb01147.x
Subject(s) - glycopyrrolate , atropine , medicine , anesthesia , thoracotomy , saline , increased heart rate , heart rate , surgery , blood pressure
Atropine, glycopyrrolate, or saline solution was administered before anesthesia in a blinded, controlled study of 40 dogs scheduled to undergo surgery. Effects of treatment on esophageal, gastric, and tracheal pH were measured with an intraluminal pH meter. Preanesthetic administration of atropine and glycopyrrolate had no effect on esophageal, gastric, or tracheal pH but did result in increased heart rate. Thoracotomy procedures resulted in decreased intraluminal esophageal pH and increased heart rate. Esophageal pH at the level of the thoracic inlet decreased over the duration of surgery.