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Postanesthetic Equine Myopathy Suggestive of Malignant Hyperthermia: A Case Report
Author(s) -
KLEIN LIN,
AILES NANCY,
FACKELMAN GUSTAVE E.,
KELLON ELEANOR,
ROSENBERG HENRY
Publication year - 1990
Publication title -
veterinary surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 79
eISSN - 1532-950X
pISSN - 0161-3499
DOI - 10.1111/j.1532-950x.1990.tb01131.x
Subject(s) - medicine , malignant hyperthermia , myopathy , dantrolene , halothane , anesthesia , horse , rhabdomyolysis , creatine kinase , paleontology , biology , calcium
Signs of malignant hyperthermia, including progressive increases in PaCO 2 , skin temperature and heart rate, and elevated serum levels of potassium, inorganic phosphate, and creatine kinase, were identified in a halothane‐anesthetized horse. Treatment was discontinuing halothane administration, applying ice and cold fluids, and hyperventilating with 100% oxygen. After an initial recovery, bilateral hindlimb myopathy and pigmenturia developed. The myopathy resolved after treatment with oral dantrolene, IV fluids, and hydrocortisone. Results of caffeine‐halothane challenge, using semimembranosus muscle collected 2 weeks after the episode, were considered within normal limits for horses. The intraoperative abnormalities were evidently predictive of postanesthetic myopathy but the cause in this horse remained unclear.