Premium
Gas Exchange during Xylazine–ketamine Anesthesia in Neonatal Calves
Author(s) -
BLAZE C. A.,
HOLLAND R. E.,
GRANT A. L.
Publication year - 1988
Publication title -
veterinary surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 79
eISSN - 1532-950X
pISSN - 0161-3499
DOI - 10.1111/j.1532-950x.1988.tb00295.x
Subject(s) - medicine , ketamine , anesthesia , hypoventilation , xylazine , arterial blood , hypoxemia , respiratory rate , heart rate , blood pressure , arterial oxygen tension , respiration , respiratory system , lung , anatomy
Ten neonatal calves were anesthetized with xylazine and ketamine intramuscularly and breathed air spontaneously. Drug injection was repeated after 45 minutes. Each injection resulted in a rapid and sustained increase in respiratory rate, but arterial carbon dioxide tension (Pa CO2 ) increased, indicating hypoventilation. Arterial hypoxemia, primarily caused by hypoventilation, developed within 15 minutes of each injection, but gradually disappeared. Acidemia was primarily respiratory in origin. Heart rate and arterial blood pressure decreased for the duration of anesthesia (90 minutes). This form of anesthesia is a satisfactory alternative to inhalation anesthesia of neonatal calves.