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Xylenol Orange as a Vital Stain to Determine the Viability of Skin Flaps in Dogs
Author(s) -
BELLAH J. R.,
KRAHWINKEL D. J.
Publication year - 1985
Publication title -
veterinary surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 79
eISSN - 1532-950X
pISSN - 0161-3499
DOI - 10.1111/j.1532-950x.1985.tb00840.x
Subject(s) - medicine , sodium fluorescein , xylenol orange , orange (colour) , staining , vital stain , stain , fluorescein , surgery , pathology , chemistry , physics , biology , horticulture , nuclear chemistry , quantum mechanics , fluorescence
Intravenous injection of xylenol orange results in generalized violet staining of vascularized skin. The precision of xylenol orange vital staining was compared to fluorescein sodium vital staining and to assessment of skin flap viability by visual observation (color). Skin flaps in the experimental dogs were evaluated by each method at 0, 24, 72, and 120 hours after surgery and subsequently compared to the length of skin flap that remained viable at 216 hours. No significant differences between methods were found at any time interval; however, assessment of skin flap viability was significantly more precise at 24,72, and 120 hours in comparison to the 0 hour assessments. The use of xylenol orange to assess vascular integrity of skin is precise, but no advantage over fluorescein sodium vital staining or assessment by visual observation was noted.