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Effect of the Association of Nystatin with a Tissue Conditioner on its Ultimate Tensile Strength
Author(s) -
Urban Vanessa Migliorini,
De Souza Raphael Freitas,
Galvao Arrais Cesar Augusto,
Borsato Karina Tostes,
Vaz Luís Geraldo
Publication year - 2006
Publication title -
journal of prosthodontics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.902
H-Index - 60
eISSN - 1532-849X
pISSN - 1059-941X
DOI - 10.1111/j.1532-849x.2006.00130.x
Subject(s) - ultimate tensile strength , nystatin , materials science , composite material , chemistry , biochemistry , antibiotics
Purpose : This study evaluated the ultimate tensile strength of a tissue conditioner without nystatin incorporation (GI—control group) and the same tissue conditioner modified by the addition of nystatin in two concentrations: GII—500,000 International Units (U) and GIII—1,000,000 U, in which each milligram of the medicament corresponded to 6079 U.Materials and Methods : Dumbbell‐shaped specimens ( N = 7) with a central cross‐sectional area of 33 × 6 × 3 mm were produced for the three experimental groups. After polymerization following manufacturer's instructions, specimens were immersed in distilled water at 37°C for either 24 hours or 7 days and then tested in tension in the MTS 810 at 40 mm/minute. Data were analyzed by two‐way ANOVA followed by Tukey's test, at 95% level of confidence.Results : The means (force‐grams (gf) ± standard deviation) of the ultimate tensile strength were: GI—634.29 ± 122.80; GII—561.92 ± 133.56; and GIII—547.30 ± 73.47 for 24‐hour storage, and GI—536.68 ± 54.71; GII—467.50 ± 143.51; and GIII—500.62 ± 159.76 for 7‐day storage. There were no statistically significant differences among the three experimental groups ( p > 0.05). The ultimate tensile strength means of all experimental groups after 7 days were significantly lower than those observed after 24 hours ( p = 0.04).Conclusions : The results of this study suggest that the addition of nystatin into the tissue conditioner investigated in concentrations below 1,000,000 U did not affect its ultimate tensile strength.