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Association Between Timed Up‐and‐Go and Memory, Executive Function, and Processing Speed
Author(s) -
Donoghue Orna A.,
Horgan N. Frances,
Savva George M.,
Cronin Hilary,
O'Regan Claire,
Kenny Rose Anne
Publication year - 2012
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.2012.04120.x
Subject(s) - montreal cognitive assessment , cognition , trail making test , medicine , effects of sleep deprivation on cognitive performance , cognitive test , verbal fluency test , cognitive decline , timed up and go test , population , audiology , univariate , memory span , mini–mental state examination , longitudinal study , gerontology , multivariate analysis , multivariate statistics , working memory , physical medicine and rehabilitation , psychiatry , dementia , neuropsychology , cognitive impairment , statistics , balance (ability) , disease , environmental health , mathematics , pathology
Objectives To determine which cognitive tests are independently associated with performance on the Timed U p‐and‐ G o T est ( TUG ). Design Data were obtained from W ave 1 of T he I rish L ongitudinal S tudy on A geing ( TILDA ), a population‐based study assessing health, economic, and social aspects of aging. Setting Community‐dwelling adults completed a home based interview and a health center–based assessment. Participants TILDA participants aged 50 and older with a M ini‐ M ental S tate E xamination ( MMSE ) score of 10 or greater (N = 4,998). Measurements Participants completed a battery of cognitive assessments including the M ontreal C ognitive A ssessment ( M o CA ), C olor T rails T est, word and letter fluency, choice reaction time, sustained attention, prospective memory, word recall, and picture memory. Linear regression was used to determine univariate and multivariate associations between TUG and each cognitive test. Results Slower TUG time was associated with poorer performance on all cognitive tests in univariate analysis ( P < .05). In multivariate analysis, poorer performance on the M o CA , letter fluency, C olor T rail 1, cognitive reaction time, mean sustained attention response time, and prospective memory were independently associated with slower TUG time ( P < .05). Conclusion Slower TUG time is independently associated with poorer performance on global cognition, executive function, and memory tests and slower processing speed. This highlights that TUG is more than just a simple mobility task and suggests that a comprehensive cognitive assessment is important for individuals with mobility difficulties.