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Depressive Symptoms and Physical Performance in the Lifestyle Interventions and Independence for Elders Pilot Study
Author(s) -
Matthews Margaret M.,
Hsu FangChi,
Walkup Michael P.,
Barry Lisa C.,
Patel Kushang V.,
Blair Steven N.
Publication year - 2011
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.2011.03319.x
Subject(s) - medicine , depression (economics) , physical therapy , geriatric depression scale , psychological intervention , randomized controlled trial , depressive symptoms , gerontology , psychiatry , anxiety , economics , macroeconomics
OBJECTIVES: To determine whether the presence of high depressive symptoms (Center for Epidemiologic Studies Depression Scale (CES‐D) score ≥14) diminished physical performance benefits after a comprehensive physical activity intervention in older adults. DESIGN: A post hoc analysis of data from the Lifestyle Interventions and Independence for Elders Pilot (LIFE‐P) study, a single‐blind randomized controlled trial comparing a moderate‐intensity physical activity intervention (PA) with a successful aging control (SA). SETTING: Multicenter U.S. institutions participating in the LIFE‐P trial. PARTICIPANTS: Four hundred twenty‐four sedentary, noninstitutionalized adults aged 70 to 89. MEASUREMENTS: Depressive symptoms were assessed using the CES‐D. Physical performance tests included the Short Physical Performance Battery (SPPB) and 400‐m walk time (400 mw) at baseline and 6 and 12 months. RESULTS: Of the participants, 15.8% had high depressive symptom scores (CES‐D ≥14). For participants with low depressive symptoms, SPPB scores improved more in the PA than the SA group over 12 months (adjusted score difference +0.70; P <.001 at 6 months and +0.58; P =.004 at 12 months), and 400 mw times improved in the PA group at 6 months (adjusted score difference −0.41 minutes; P =.02). For participants with high depressive symptoms, the difference in improvement fell short of statistical significance on the SPPB between the PA and SA groups (adjusted score difference +0.76 ( P =.18) at 6 months and +0.94 ( P =.12) at 12 months). CONCLUSION: The presence of high depressive symptoms did not substantially diminish physical performance benefits realized after a PA intervention in sedentary older adults.