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NEUROIMAGING IN DEMENTIA
Author(s) -
Murden Robert A.
Publication year - 2011
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.2011.03253.x
Subject(s) - medical diagnosis , medicine , dementia , neuroimaging , radiological weapon , disease , intensive care medicine , psychiatry , pediatrics , radiology , pathology
model could be developed, but the focus of the article was to fully describe the development of a frailty measure that will inform further research in full prediction models. A range of patient characteristics (clinical, cognitive, and psychosocial) is being examined to develop a full prediction model for functional decline at 30 months postprocedure. Regarding treatment type (CABG, PCI, or medical) and functional outcomes, no statistically significant relationship was found between treatment and the likelihood of decline at 12 months in function or health-related quality of life. In addition, treatment type neither modified nor confounded the relationship between the frailty index and either outcome. With regard to model performance, the Hosmer-Lemeshow test for the final 5-variable model (shown in Table 2 of the previous article) yielded a P-value of .76, indicating that calibration was good. This model was simplified by assigning indicators for the presence or absence of each of the criteria, giving each variable equal weight. Table 3 showed the results of modeling a 2 4 contingency table using the frailty score categories of 0, 1, 2, and 3 or more. This approach models the proportions exactly, so the predicted (or fitted) and observed risks are the same. We hope that this response has helped clarify the concerns brought forward by Dr. Kim and Ms. Choi. We thank them for their interest in our research.