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Old Age and Outcome After Primary Angioplasty for Acute Myocardial Infarction
Author(s) -
de Boer MenkoJan,
Ottervanger Jan Paul,
Suryapranata Harry,
Hoorntje Jan C.A.,
Dambrink JanHenk E.,
Gosselink A.T. Marcel,
van't Hof Arnoud W.J.,
Zijlstra Felix
Publication year - 2010
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.2010.02821.x
Subject(s) - medicine , conventional pci , myocardial infarction , percutaneous coronary intervention , odds ratio , confidence interval , retrospective cohort study , multivariate analysis , angioplasty , risk factor , surgery
OBJECTIVES: To assess the influence of age as an independent factor determining the prognosis and outcome of patients with acute myocardial infarction (AMI) treated using primary percutaneous coronary intervention (PCI). DESIGN: A retrospective analysis from a dedicated database. SETTING: A high‐volume interventional cardiology center in the Netherlands. PARTICIPANTS: Four thousand nine hundred thirty‐three consecutive patients with AMI. MEASUREMENTS: Baseline characteristics and clinical outcomes after 30 days and 1 year were compared according to age categorized in three groups: younger than 65, 65 to 74, and 75 and older. A more‐detailed analysis was performed with six age groups, from younger than 40 to 80 and older. RESULTS: Of the 4,933 consecutive patients with AMI treated with PCI between 1992 and 2004, 643 were aged 75 and older. Multivariate analysis revealed that patients aged 65 to 75 had a greater risk of 1‐year mortality than those younger than 65 (adjusted odds ratio (AOR)=1.57, 95% confidence interval (CI)=1.15–2.16) and that those aged 75 and older had a greater risk of 1‐year mortality than those younger than 65 (AOR=3.03, 95% CI=2.14–4.29). CONCLUSION: In this retrospective analysis, older age was independently associated with greater mortality after PCI for AMI. Patients aged 65 and older had a higher risk of mortality than younger patients, and those aged 75 and older had the highest risk of mortality.