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PREVALENCE AND RISK FACTORS OF PERIPHERAL ARTERIAL DISEASE AMONG OLDER PATIENTS LIVING IN NURSING HOMES
Author(s) -
Bo Mario,
Zanocchi Mauro,
Gallo Raffaela,
Bergoglio Isa,
Poli Leone,
Fabris Fabrizio
Publication year - 1996
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1996.tb01851.x
Subject(s) - medicine , disease , arterial disease , diabetes mellitus , ankle , activities of daily living , physical therapy , gerontology , vascular disease , surgery , endocrinology
decreased elimination half-life, probably attributable to the early gastric lavage associated with repeated instillation of active charcoal, both of which reduce enteral absorption of drugs Continuous IV infusion of flumazenil was shown to be a better mode of treatment'v" than boluses, both because of its short half-life" (54 minutes) and the wish to avoid patient fluctuations in and out of coma. Rectal administration has recently been mentioned as a safe alternative regimen." Longterm enteral administration, here described for the first time, was easy to carry out, obviated placement of IV lines, had a rapid onset, was as efficaciousas the IV mode, was less costly, and was free from physical or mental side effects. Although not yet available in many countries, oral flumazenil administration has the potential to become the long-term treatment of choice for benzodiazepine-induced coma, especially in patients who are alternately awake and relapsing into coma.

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