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Prostaglandin E 1 as Treatment for Erectile Failure in Elderly Men
Author(s) -
Godschalk Michael F.,
Chen Juza,
Katz P. Gary,
Mulligan Thomas
Publication year - 1994
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1994.tb06508.x
Subject(s) - medicine , prostaglandin e1 , erectile dysfunction , palpation , penis , prostaglandin , surgery
OBJECTIVE: To determine the efficacy of intracavernosal injection of prostaglandin E 1 (alprostadil) in elderly men with erectile failure. DESIGN: Prospective study. SETTING: Outpatients at a university‐affiliated VA Medical Center. PARTICIPANTS: Ten subjects aged 65 years and older with duration of erectile failure of 6 months or longer. INTERVENTIONS: Subjects received intracavernosal injections of prostaglandin E 1 in the office and self‐administered intracavernosal prostaglandin E 1 at home. MEASUREMENTS: Penile rigidity was measured by palpation and by the Rigiscan rigidity monitor. RESULTS: Intracavernosal injection of prostaglandin E 1 produced erections adequate for intercourse in 9 of the 10 subjects. Attempts at intercourse were rated satisfactory by two‐thirds of the subjects and their spouses. CONCLUSIONS: Intracavernosal injection of prostaglandin E 1 is safe and effective for erectile failure in elderly men.