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TRH Tests in a Healthy Elderly Population
Author(s) -
Targum Steven D.,
Marshall Lois E.,
MagacHarris Kelly,
Martin David
Publication year - 1989
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1989.tb05685.x
Subject(s) - medicine , gerontology
Thyrotropin releasing hormone (TRH) tests were conducted in 99 healthy elderly men and women between the ages of 65 and 89. The TRH test identified elderly patients with subclinical thyroid dysfunction not recognized by basal TSH values alone. Men revealed significantly diminished TSH responses to TRH injection relative to women. Mean Δ max TSH was 9.0 ± 8.3 μIU/mL in men vs 15.7 ± 14.8 μIU/mL in women (P < .01) reflecting the need to consider gender effect in the interpretation of TRH test responses.