Premium
Metabolic Changes in Alzheimer's Disease
Author(s) -
Fisman Michael,
Gordon Bruce,
Feleki Vera,
Helmes Edward,
McDonald Thomas,
Dupre John
Publication year - 1988
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1988.tb02354.x
Subject(s) - medicine , alzheimer's disease , insulin , endocrinology , glucagon , disease , diabetes mellitus
Patients with Alzheimer's disease (AD) and matched controls fasted for 24 hours, and serial glucose, pyruvate, lactate, β‐hydroxybutyrate, acetoacetate, insulin, and glucagon levels were measured. Patients with AD showed a glucose insulin correlation pattern over the 24 hours that differed from the control group. These differences may be secondary to weight loss or to other metabolic or nutritional factors affecting the AD patients.