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Myasthenia Gravis in the Elderly: Report of 37 Cases
Author(s) -
EVOLI AMELIA,
TONALI PIETRO,
SCOPPETTA CIRIACO,
DAVID PASQUALE
Publication year - 1983
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1111/j.1532-5415.1983.tb05746.x
Subject(s) - medicine , myasthenia gravis , thymectomy , surgery , pediatrics , disease
The treatment of myasthenia gravis in the elderly is controversial. Thirty‐seven myasthenic patients with onset of the disease after the age of 60 were followed for a period of 14 years. All of the 37 patients received anticholinesterase drugs during this period, ten underwent thymectomy, and 24 were treated with corticosteroids. At present, one patient is in remission, 28 are improved, one is unchanged, and seven have died. Only one death was directly related to myasthenia. In the authors' experience thymectomy can be an effective treatment of myasthenia gravis in elderly patients; corticosteroid therapy can also be useful in addition to or as an alternative to surgery. Using a “personalized” schedule the authors obtained good results in 78 per cent of their patients.